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Vulnerability Intelligence

CVE-2021-42321

HighExploitedPublic exploit

Microsoft Exchange Server Remote Code Execution Vulnerability

Published Mar 2, 2022 · Updated Aug 19, 2026 · Also known as TR-21-0903, TR-22-0188

Key Facts

Patch immediately
  • CVE-2021-42321 is a high-severity vulnerability (CVSS 8.8 v3.1) affecting Exchange Server (Microsoft), Microsoft Exchange Server 2016 Cumulative Update 21, Microsoft Exchange Server 2016 Cumulative Update 22 and 2 more products.
  • It is exploited in the wild, listed in CISA KEV, Industry KEV feed, CIRCL KEV, ENISA EUVD since Nov 9, 2021 and is known to be used in ransomware campaigns. Public exploit code is available.
  • EPSS estimates a 92% probability of exploitation in the next 30 days.
  • Fixed versions are available, including Exchange Server 15.01.2308.020, Exchange Server 15.01.2375.017, Exchange Server 15.02.0792.019.
  • Brandefense priority: patch immediately, because it is listed as exploited in the wild.

CVSS v3.1

8.8

CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H

EPSS (30-day exploit likelihood)

92%

Higher than 99.8% of all scored CVEs

Exploited in the wild

Yes

4 catalog listings, used by ransomware

Public exploit code

Available

Proof-of-concept or weaponized module

Get the full CVE-2021-42321 brief as a PDF

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Description

Microsoft Exchange Server Remote Code Execution Vulnerability

Known-Exploited Catalog Listings

CatalogAddedRemediation dueRansomware use
CISA KEVNov 17, 2021Dec 1, 2021Known
Industry KEV feedNov 9, 2021Dec 1, 2021Known
CIRCL KEVNov 17, 2021Dec 1, 2021Known
ENISA EUVDNov 17, 2021n/aNot reported

Required action: Apply updates per vendor instructions.

Affected Products

12 affected entries in total
ProductAffected versionsFixed in
Exchange ServerMicrosoft2016-cumulative_update_21, 2016-cumulative_update_22, 2019-cumulative_update_10, 2019-cumulative_update_1115.01.2308.020
Microsoft Exchange Server 2016 Cumulative Update 21>= 15.01.015.01.2308.020
Microsoft Exchange Server 2016 Cumulative Update 22>= 15.0.015.01.2375.017
Microsoft Exchange Server 2019 Cumulative Update 10>= 15.02.015.02.0792.019
Microsoft Exchange Server 2019 Cumulative Update 11>= 15.02.015.02.0986.014

Patched Releases

Exchange Server

15.01.2308.020, 15.01.2375.017, 15.02.0792.019, 15.02.0986.014

Microsoft Exchange Server 2016 Cumulative Update 21

15.01.2308.020

Microsoft Exchange Server 2016 Cumulative Update 22

15.01.2375.017

Microsoft Exchange Server 2019 Cumulative Update 10

15.02.0792.019

Microsoft Exchange Server 2019 Cumulative Update 11

15.02.0986.014

Timeline

  1. Added to Industry KEV feed

    Nov 9, 2021

  2. Added to CISA KEV

    Nov 17, 2021

  3. Added to CIRCL KEV

    Nov 17, 2021

  4. Added to ENISA EUVD

    Nov 17, 2021

  5. Publicly disclosed

    Mar 2, 2022

  6. Last updated

    Aug 19, 2026

References

15 more references in the full CVE brief

FAQ

Common Questions.

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